ANALYSIS OF LOW MOLECULAR WEIGHT MOLECULES BY MALDI-MS
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United States of America Patent
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Issued Date -
Apr 1, 2010
app pub date -
Mar 19, 2008
filing date -
Mar 20, 2007
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Abandoned
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Abstract
The invention relates to a process for the analysis of molecules having a molecular weight of <1500 Da by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), wherein an analyte containing low molecular weight molecules is applied to a matrix material, which is characterized in that the matrix material comprises fullerene-derivatised silica. This process allows clear identification of small molecules through intensive signals without matrix -related background disturbances.
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