Cyclopropane compounds and pharmaceutical use thereof
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United States of America Patent
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app pub date -
Jun 9, 2009
filing date -
Dec 15, 2003
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Abandoned
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Abstract
The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula (1):is a hydrogen atom, etc.; or a prodrug thereof or a pharmaceutically acceptable salt thereof.
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