Composite material for use as protein carrier
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United States of America Patent
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Issued Date -
May 6, 2010
app pub date -
Jun 9, 2005
filing date -
Jun 9, 2004
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to a material having osteoinductive and osteoconductive properties in vivo comprising a ceramic carrier, preferably containing calcium phosphate, and an active agent, preferably an osteoinductive protein/peptide or a drug, and a polymer, wherein the active agent is homogeneously coated on the carrier and within the polymer, which is preferably a degradable polymer. Said polymer modulates the release kinetic of the active agent and protects same from degradation to prolong the half-life in vivo. Moreover, the present invention relates to a method for the production of a material having osteoinductive and osteoconductive properties in vivo.
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