Purification of acidic proteins using ceramic hydroxyapatite chromatography

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United States of America Patent

PATENT NO 8058407
APP PUB NO 20100113751A1
SERIAL NO

12608093

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Abstract

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The present invention provides a method of removing product-related inactive or partially active species, high molecular weight aggregates, as well as other process-related impurities from preparations of acidic proteins by using ceramic hydroxyapatite chromatography.

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Patent Owner(s)

  • WYETH LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jennings, Priscilla Wilmington, US 1 49
Luo, Yin Cambridge, US 3 49
Sun, Shujun Brentwood, US 13 391

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