HIGH AFFINITY EPHB RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF
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United States of America Patent
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Issued Date -
Jun 17, 2010
app pub date -
Sep 14, 2007
filing date -
Sep 15, 2006
priority date (Note) -
Abandoned
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Abstract
The present invention provides peptide-based compounds that selectively bind to a member(s) of the EphB receptor family, including, but not limited to, EphB1, EphB2, EphB3, EphB4, EphB5 and EphB6. In particular, the invention provides multimeric peptides that selectively bind to EphB receptors. The present invention also provides compositions, including pharmaceutical compositions, comprising the EphB receptor binding compounds and a pharmaceutically acceptable carrier or excipient. Methods for identifying compounds that selectively or specifically bind to a member of the EphB receptor family are also provided.
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