ENGINEERED PHOSPHITE DEHYDROGENASE MUTANTS

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United States of America Patent

APP PUB NO 20100151529A1
SERIAL NO

12595807

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Abstract

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Phosphite dehydrogenase mutant enzymes provide relaxed cofactor specificity, increased thermostability, increased activity, solubility, and expression over the wild-type enzyme. The mutant enzymes are useful for nicotinamide cofactor regeneration.

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Patent Owner(s)

Patent OwnerAddress
BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION1815 NORTH UNIVERSITY STREET PEORIA IL 61604

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johannes, Tyler Stillwater, US 2 6
McLachlan, Michael Urbana, US 5 39
Zhao, Huimin Champaign, US 44 196

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