DIAGNOSIS AND TREATMENT OF DISEASES CAUSED BY MISFOLDED PROTEINS
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United States of America Patent
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Issued Date -
Jul 1, 2010
app pub date -
Apr 11, 2008
filing date -
Apr 11, 2007
priority date (Note) -
Abandoned
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Abstract
In certain aspects, the disclosure relates to methods and compositions for diagnosing and treating diseases caused by misfolded proteins that comprise monitoring ANKRD 16 expression and altering the activity of ANKRD 16 protein. In certain embodiments, the diseases are neurodegenerative diseases. In certain embodiments, the diseases are proteopathies. In certain embodiments, the disease is reduced fertility. Methods for identifying agents that protect against cell death are also provided.
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