US Patent Application No: 2010/0172,843

Number of patents in Portfolio can not be more than 2000

NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION

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Abstract

A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATIONCOLUMBUS, OH780

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kuppusamy, Periannan New Albany, OH 7 5
Pandian, Ramasamy P Columbus, OH 3 5
Parinandi, Narasimham L Upper Arlington, OH 3 5
Zweier, Jay L Blacklick, OH 9 7

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (1)
8,066,973 Nanoparticulate probe for in vivo monitoring of tissue oxygenation 0 2006