Methods and compositions for post-transcriptional gene silencing

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United States of America Patent

APP PUB NO 20100186102A1
SERIAL NO

12673575

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Abstract

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An isolated double stranded ribonucleic acid (dsRNA) molecule that inhibits the expression of a target gene, the dsRNA comprising two strands of nucleotides wherein a first strand has a length of from 19 to 28 consecutive nucleotides and is substantially identical to a sequence in the target gene and wherein a second strand is substantially complementary to the first strand, and a binding moiety that binds a 3′ end of the first strand to a 5′ end of the second strand. An isolated double stranded ribonucleic acid molecule comprising a first strand of nucleotides that is substantially identical to SEQ ID NO: 3 and a second strand that is substantially complementary to the first.

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Patent Owner(s)

Patent OwnerAddress
SCOTT AND WHITE HEALTHCARE2401 SOUTH 31ST STREET TEMPLE TX 76508

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Asea, Alexzander Belton, US 3 3

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