CETP ACTIVITY INHIBITORS
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United States of America Patent
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app pub date -
Jul 13, 2009
filing date -
Feb 12, 1997
priority date (Note) -
Abandoned
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Abstract
The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I):—, and Z represents a hydrogen atom or a mercapto-protecting group, or a prodrug compound, a pharmaceutically acceptable salt, or hydrate or solvate thereof. The compounds represented by the formula (I) can increase HDL and at the same time decrease LDL through selective inhibition of CETP activity and, therefore, is expected to be useful as a new type of a preventive or therapeutic agent for atherosclerosis or hyperlipidemia.
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