Therapeutics for Cancer Using 3-Bromopyruvate and Other Selective Inhibitors of ATP Production
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United States of America Patent
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Aug 12, 2010
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Dec 17, 2007
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Dec 18, 2006
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Abstract
The present invention relates to methods of treating a cancerous tumor in a subject comprising administering to the subject an effective amount of 3-bromopyruvate. The 3-bromopyruvate may be administered intraarterially directly to a tumor as a continuous intraarterial infusion. The present invention also relates to methods for identifying agents that inhibit type II hexokinase activity.
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