Polyphenol Conjugates as RGD-Binding Compounds and Methods of Use
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United States of America Patent
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Issued Date -
Aug 19, 2010
app pub date -
Sep 18, 2006
filing date -
Sep 16, 2005
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Abstract
Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol.
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