US Patent Application No: 2010/0209,458

Number of patents in Portfolio can not be more than 2000

AMPHIPHILIC MOLECULE, MOLECULAR ASSEMBLY COMPRISING THE AMPHIPHILIC MOLECULE, AND USE OF THE MOLECULAR ASSEMBLY

ALSO PUBLISHED AS: 8241647

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. According to a preferred embodiment of the present invention, the molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
JCR PHARMACEUTICALS CO., LTD.HYOGO55
WASEDA UNIVERSITYTOKYO83

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ito, Manabu Saitama, JP 65 2232
Mizuno, Atsushi Yokohama, JP 49 229
Nishiyama, Natsuko - 2 0
Obata, Yosuke Yokkaichi, JP 9 7
Tajima, Shoji Higashikana, JP 6 36
Takeoka, Shinji Tokyo-to, JP 83 134
Takeuchi, Yoshito - 2 0

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