US Patent Application No: 2010/0209,458

Number of patents in Portfolio can not be more than 2000

AMPHIPHILIC MOLECULE, MOLECULAR ASSEMBLY COMPRISING THE AMPHIPHILIC MOLECULE, AND USE OF THE MOLECULAR ASSEMBLY

ALSO PUBLISHED AS: 8241647

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention provides an amphiphilic molecule having a plurality of zwitterionic functional groups in its hydrophilic moiety and a molecular assembly comprising the amphiphilic molecule as a constituent lipid. According to a preferred embodiment of the present invention, the molecular assembly of the present invention forms a stable vesicular structure under a physiological pH environment to carry a substance of interest in the vesicular structure, and can release the substance of interest to the outside of the vesicular structure when it is deformed under an acidic pH environment. The molecular assembly of the present invention can be used as a carrier for a drug, a probe, a nucleic acid, a protein or the like.

Loading the Abstract Image... loading....

First Claim

See full text

all claims..

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
JCR PHARMACEUTICALS CO., LTD.HYOGO43
WASEDA UNIVERSITYTOKYO72

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ito, Manabu Saitama, JP 65 2494
Mizuno, Atsushi Yokohama, JP 49 233
Nishiyama, Natsuko - 2 0
Obata, Yosuke Yokkaichi, JP 9 7
Tajima, Shoji Higashikana, JP 6 36
Takeoka, Shinji Tokyo-to, JP 84 142
Takeuchi, Yoshito - 2 0

Cited Art Landscape

Patent Info (Count) # Cites Year
 
JCR PHARMACEUTICALS CO., LTD. (2)
* 2004/0162,261 Zwitterionic lipid compound and uses thereof 1 2004
* 6,965,049 Zwitterionic lipid compound and uses thereof 2 2004
 
WASEDA UNIVERSITY (2)
* 2002/0120,096 Amphiphilic compounds having a dendritic branch structure 2 2002
* 6,933,352 Amphiphilic compounds having a dendritic branch structure 2 2002
 
MARINA BIOTECH, INC. (1)
* 7,939,505 Amino acid lipids and uses thereof 2 2008
 
UNIVERSITY OF KANSAS (1)
* 5,998,482 Use of synthetic polycationic amphiphilic substances with fatty acid or hydrocarbon substituents as anti-sepsis agents 3 1998
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

  • No Forward Cites to Display