ENZYMATIC NUCLEIC ACID SYNTHESIS: METHODS FOR DIRECT DETECTION OF TAGGED MONOMERS

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United States of America Patent

SERIAL NO

12352353

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Abstract

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Nucleotide triphosphate probes containing a molecular and/or atomic tag on a γ and/or β phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.

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Patent Owner(s)

Patent OwnerAddress
LIFE TECHNOLOGIES CORPORATION5823 NEWTON DRIVE ATTN IP DEPARTMENT CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Briggs, James Katy, US 39 2165
Gao, Xiaolian Houston, US 68 2901
Hardin, Susan H College Station, US 22 979
Tu, Shiao-Chun Houston, US 36 2005
Willson, Richard Houston, US 48 2132

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