SUSTAINED-RELEASE FORMULATIONS
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United States of America Patent
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Issued Date -
Sep 2, 2010
app pub date -
Dec 30, 2009
filing date -
Dec 31, 2008
priority date (Note) -
Abandoned
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Abstract
Described herein are extended-release or sustained-release formulations suitable for highly soluble pharmacologically active compounds, for example, amantadine. Dosage units for providing extended release are provided by the present invention. In some embodiments, the dosage unit comprises a plurality of coated beads having drug layer and a coating layer, wherein the coating layer comprises an ethylcellulose polymer. In some embodiments, near zero-order release of the active compound is achieved.
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