Pharmaceutical Compositions for the Treatment of TNF-Alpha Related Disorders

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United States of America Patent

SERIAL NO

12693225

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Abstract

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The invention relates to a pharmaceutical composition comprising a variant TNF-α protein that inhibits the activity of soluble TNF-α while substantially maintaining the activity of transmembrane TNF-α, a buffer, and a tonicity agent, wherein said composition has a pH from approximately 5.0 to 8.0.

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Patent Owner(s)

Patent OwnerAddress
XENCOR INC465 NORTH HALSTEAD STREET SUITE 200 PASADENA CA 91107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carmichael, David F Monrovia, US 20 340
Desjarlais, John R Pasadena, US 195 6468
Steed, Paul Michael Chapel Hill, US 6 66
Szymkowski, David Edmund Monrovia, US 8 67
Zalevsky, Jonathan Riverside, US 30 304

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