Treatment of Malignant Peripheral Nerve Sheath Tumors
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United States of America Patent
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Issued Date -
Sep 2, 2010
app pub date -
Nov 11, 2009
filing date -
Nov 14, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention pertains to a combination comprising (a) at least one c-Jun N-terminal kinase (JNK) inhibitor and (b) 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pyrimidylaminobenzamide of formula Iwherein the radicals and symbols are as defined herein, or, respectively, a pharmaceutically acceptable salt thereof, and its use for the manufacture of a pharmaceutical composition for the treatment of malignant peripheral nerve sheath tumors.
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