TREATMENT REGIME FOR PROLIFERATIVE DISORDERS

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United States of America Patent

SERIAL NO

12678851

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are methods for treating or ameliorating a proliferative disorder in a subject. The method contains the steps of administering to the subject one dose of an immunosuppressive agent followed by administering to the subject one to five doses of a reovirus. The immunosuppressive agent is administered to the subject at least about 72 hours prior to administration of the reovirus. Also provided herein are methods for treating or ameliorating a proliferative disorder in a subject including the steps of administering to the subject an oncolytic virus and a B-cell modulating agent. Also provided are kits and pharmaceutical compositions containing an oncolytic virus and at least one B-cell modulating agent.

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Patent Owner(s)

Patent OwnerAddress
ONCOLYTICS BIOTECH INCCALGARY ALBERTA T2N 1X7

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coffey, Matthew C Calgary, CA 88 836
Thompson, Bradley G Calgary, CA 84 747

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