Methods and compositions for treating neuropathic and neurodegenerative conditions
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United States of America Patent
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app pub date -
Oct 8, 2009
filing date -
Apr 8, 2004
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Abstract
Disclosed herein are engineered zinc finger proteins which modulate transcription of the gene encoding vascular endothelial growth factor-A (VEGF-A) and other genes encoding products with neurotrophic activities. Also disclosed are methods for the use of these engineered zinc finger proteins in the treatment of neuropathy (including diabetic neuropathy), and other types of neural injury and neurodegeneration.
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