Methods for determining cytosine methylation in DNA and uses thereof

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United States of America Patent

PATENT NO 8642294
APP PUB NO 20100267021A1
SERIAL NO

12451431

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Abstract

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Methods are described for determining the pattern of cytosine methylation in a DNA specimen, where the methods involve comparing the amount of DNA fragments generated by a methylation-sensitive restriction enzyme with the amount of DNA fragments generated by a methylation-insensitive isoschizomer of the methylation-sensitive restriction enzyme.

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Patent Owner(s)

Patent OwnerAddress
ALBERT EINSTEIN COLLEGE OF MEDICINE1300 MORRIS PARK AVENUE BRONX NY 10461

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greally, John M New York, US 1 0
Hatchwell, Eli St. James, US 42 1329

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