Pulmonary delivery particles comprising an active agent
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United States of America Patent
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Jan 31, 2017
Grant Date -
Oct 28, 2010
app pub date -
May 5, 2010
filing date -
Sep 29, 1997
priority date (Note) -
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Abstract
A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 μm. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.
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