TARGETED NANOPARTICLES FOR INTRACELLULAR CANCER THERAPY
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United States of America Patent
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Issued Date -
Nov 11, 2010
app pub date -
May 10, 2010
filing date -
May 8, 2009
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This invention provides constructs comprising a targeting member immobilized on a detectable particulate, in which binding of the targeting member to a target structure on a surface of a cancer cell triggers internalization of the construct. Such constructs can be used to identify or monitor cancer cells in cell cultures or in a tissue. Such construct can also be used to kill or prevent growth of cancer cells in vivo. Also included in the invention are methods for killing or preventing growth of cancer cells in vivo.
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