Non-Ribosomal Peptide Synthetases

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United States of America Patent

SERIAL NO

12819751

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Abstract

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Novel tailor-made artificial non-ribosomal peptide synthetases (NRPSs) for non-ribosomal synthesis and/or modification of peptides of a predetermined length and composition and/or for modification of individual amino acids are described. The fusion of building units of said peptide synthetases in particular linker regions makes it possible to specifically prepare by means of “modular molecule construction kits” NRPSs which are capable of synthesizing peptides of a desired structure.

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Patent Owner(s)

Patent OwnerAddress
CUBIST PHARMACEUTICALS INC65 HAYDEN AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dokel, Sascha Cambridge, US 1 1
Linne, Uwe Rosenthal, DE 2 7
Marahiel, Mohamed A Marburg, DE 5 28
Mootz, Henning New York, US 4 9
Schwarzer, Dirk Marburg, DE 3 15

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