Proteinaceous binding molecules comprising purification tags or inert variable domains
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United States of America Patent
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Issued Date -
Nov 18, 2010
app pub date -
Jan 21, 2009
filing date -
Jan 21, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention provides proteinaceous binding molecules, in particular antibodies, having at least two variable domains. One variable domain binds to a target molecule of interest. At least one other variable domain comprises a purification tag suitable for purification of said proteinaceous binding molecule. The purification tag enables the convenient purification of the proteinaceous binding molecule with monovalent binding properties against the target molecule.
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