Involvement of Lipid Kinase, and Signal Transduction Pathway Comprising Said Lipid Kinase, in Resistance to HER2-Targeting Therapy

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United States of America Patent

APP PUB NO 20100297624A1
SERIAL NO

12595587

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Abstract

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The invention is related to a method for determining whether an individual suffering from cancer is at risk of exhibiting or acquiring a reduced response towards HER2-targeting therapy. In one aspect, the invention utilizes the activity of a signal transduction pathway modulated by a lipid kinase for determining said risk.

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Patent Owner(s)

Patent OwnerAddress
STICHTING HET NEDERLANDS KANKER INSTITUUT1066 CX AMSTERDAM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernards, Rene Abcoude, NL 35 466
Berns, Katrien Bloemendaal, NL 2 0

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