LIPOSOME MEDIATED DELIVERY OF LINEAGE DETERMINING FACTORS
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United States of America Patent
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Issued Date -
Dec 9, 2010
app pub date -
Jan 8, 2010
filing date -
Jan 9, 2009
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Abstract
Methods and compositions are provided for lineage predetermination of cellular transplants including through liposome mediated transfection with aqueous protein extracts from populations of differentiated mammalian cells, or cellular fractions thereof, wherein the differentiated mammalian cells are enriched in one or more of adipocytes, chondrocytes, endothelial cells, hepatocytes, cardiomyocytes, smooth muscle cells, skeletal muscle cells, cardiac pacemaker cells, Schwann cells, pancreatic islet cells, hematopoietic cells, myeloblasts, neurons, and osteoblasts.
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