COATED SURFACE FOR CELL CULTURE
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United States of America Patent
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Issued Date -
Dec 9, 2010
app pub date -
Apr 27, 2003
filing date -
Apr 27, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention makes available a keratin coating of a support substrate and a method for the production thereof. This keratin coating is suitable particularly for the in vitro or in vivo culturing of epithelial or endothelial cells and, because of its optical transparency, for microscopy. The keratin coating is prepared by applying or coating keratin in the form of nanoparticles from an aqueous keratin solution or keratin suspension. The solution or suspension does not contain any reducing compounds. The keratin solution is prepared preferably from hair, such as human hair. For the preparation of the coating, keratin is brought into solution or into a suspension of nanoparticles by mixing the keratin with an aqueous composition which contains thiourea, urea, and mercaptoethanol.
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