Importance

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Abstract

Electrodes, particularly electrochemically active electrodes, may benefit from one or more pretreatment cycles in which the electrode is substantially oxidized, reduced or otherwise exhausted prior to use in an end use application, for example active agent delivery via iontophoresis. For instance, electrode lifetime may be advantageously increased, even when used to delivery relatively high currents or used at high current densities. Such may be necessary to delivery therapeutically effect dosage regimes, for instance of oxycodone. Use of a nonwoven fibrous substrate printed with a sacrificial ink may be advantageous relative to other substrates. Use of certain Ag/AgCl inks may be advantageous over other Ag/AgCl inks.

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First Claim