Display Vectors and Methods and Uses Thereof
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United States of America Patent
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Issued Date -
Dec 16, 2010
app pub date -
Jan 9, 2009
filing date -
Jan 11, 2008
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates, in one aspect, to a vector comprising (a) a first polynucleotide capable of encoding a first (poly)peptide comprising at least one cysteine residue, and (b) a second polynucleotide capable of encoding a second (poly)peptide which is a cell surface anchor comprising at least one cysteine residue, wherein the vector is operable in a eukaryotic host cell to express and to cause or allow the attachment of said first (poly)peptide to said second (poly)peptide by formation of a disulfide bond between said cysteine residues comprised within said first (polypeptide and said second (poly)peptide, respectively, wherein said first (poly)peptide is exhibited at the surface of a eukaryotic host cell.
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