STEM-LIKE CELLS, METHOD FOR DE-DIFFERENTIATING MAMMALIAN SOMATIC CELLS INTO STEM-LIKE CELLS, AND METHOD FOR DIFFERENTIATING STEM-LIKE CELLS

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United States of America Patent

APP PUB NO 20100330063A1
SERIAL NO

12519499

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Abstract

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A new use is provided for small molecule inhibitors of Oct4 and Sox 2 as a cellular reprogramming agent and a method of reprogramming adult mammalian somatic cells into stem-like cells is provided, using small molecule inhibitors of Oct4 and Sox 2 without the need of any material derived from embryos or fetuses, and without the need of potentially harmful transfecting vectors. Stem-like cells created by the present invention can be induced to differentiate into terminally differentiated adult somatic cells, such as, for example, neuronal cells.

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Patent Owner(s)

Patent OwnerAddress
GLIAMED INCDOBBS FERRY NY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Weinstein, David E Dobbs Ferry, US 14 45

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