Method for identifying compounds for treatment of pain

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United States of America Patent

PATENT NO 8173376
APP PUB NO 20100330586A1
SERIAL NO

12722938

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Abstract

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Methods and products for the attenuation or treatment of pain and the reduction of nociception are described. The methods and products are based on the modulation of CNS intracellular chloride levels. The methods and products may also relate to modulation of the activity and/or expression of a chloride transporter, such as the KCC2 potassium-chloride cotransporter. Also described herein are commercial packages and uses based on such modulation. Related methods for identifying or characterizing a compound for the treatment of pain, the reduction of nociception and the diagnosis and prognostication of pain are also described.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITE LAVAL2325 RUE DE LUNIVERSITE QUEBEC CITY G1V 0A6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coull, Jeffrey A M Toronto, CA 4 8
De, Koninck Paul Cap Rouge, CA 2 9
De, Koninck Yves Ste-Foy, CA 7 67

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