Pharmaceutical Formulations for Iontophoretic Delivery of an Immunomodulator
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United States of America Patent
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Issued Date -
Dec 30, 2010
app pub date -
Jun 29, 2010
filing date -
Jun 29, 2009
priority date (Note) -
Abandoned
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Abstract
The present invention describes pharmaceutical formulations and methods suitable for iontophoretic delivery of the formulations to a subject. The formulations comprise an immunomodulator, such as imiquimod, and optionally include various agents and excipients. The formulations can be used as a treatment for skin diseases and conditions such as actinic keratosis, basal cell carcinoma and genital warts. The short term iontophoretic delivery of the formulations results in the creation of a depot effect in the skin of the subject, allowing for a sustained delivery. The shortened delivery time minimizes local side effects at the application site.
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