N-SULPHONYLATED AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF

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United States of America Patent

SERIAL NO

12829185

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Abstract

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The present invention relates to N-sulfonylated amino acid derivatives, where an aryl radical is linked via the sulfonyl group N-terminally to the amino acid and a radical which comprises at least one imino group and at least one further basic group which represents an optionally modified amino, amidino or guanidino group is linked C-terminally via the carbonyl group. The invention likewise relates to processes for preparing these compounds and to their use, in particular as inhibitors of matriptase.

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Patent Owner(s)

Patent OwnerAddress
THE MEDICINES COMPANY (LEIPZIG) GMBHLEIPZIG GERMANY LEIPZIG FREE STATE OF SAXONY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Schweinitz, Andrea Jena, DE 18 142
Stürzebecher, Anne Weimar, DE 3 19
Stürzebecher, Jörg Erfurt, DE 9 32
Steinmetzer, Torsten Jena, DE 20 504
Uhland, Kerstin Grafelfing, DE 3 26

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