USE OF CELLS TO FACILITATE TARGETED DELIVERY OF NANOPARTICLE THERAPIES
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United States of America Patent
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app pub date -
Jul 9, 2008
filing date -
Jul 9, 2007
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Abstract
The present invention is related to the use of cells, such as stem cells or immune system cells, to deliver nanogels comprising an active agent to a desired site in the body. The present invention utilizes cells as a delivery system for active agents that are difficult to deliver, such as active agents with poor solubility, that degrade easily, or that are toxic to the body. The nanogels are preferably non-toxic and can optionally include a lytic agent to program apoptosis of the cell to deliver the nanogel and active agent to a desired sire within the body.
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