GENETIC DETECTION OF HIV-1 STRAINS THAT USE THE CXCR4 CO-RECEPTOR
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United States of America Patent
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Issued Date -
Jan 27, 2011
app pub date -
Mar 20, 2009
filing date -
Mar 21, 2008
priority date (Note) -
Abandoned
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Abstract
The invention relates to a method for obtaining clonal HIV-1 sequence information from a clinical isolate derived from an HIV-1 infected individual to guide highly active anti-retroviral therapy (HAART) comprising the following steps; a) extracting cell-associated viral nucleic acid b) amplifying said nucleic acid c) obtaining clonal sequence information d) interpreting the clonal sequence information and determining the ratio of the minority viral species by bio-informatics means whereby the ratio obtained is used to guide HAART.
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