Transgenic Animal Model of Cancer and Methods of Use
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United States of America Patent
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Issued Date -
Feb 3, 2011
app pub date -
Apr 9, 2009
filing date -
Apr 11, 2008
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Abandoned
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Abstract
The invention features a transgenic mouse model of cancer, exemplified by basal cell carcinoma, which finds use in identification of anti-cancer drugs. The transgenic mouse is characterized by a heterozygous defect in a Patch gene (Ptch.sup.+/-) and an inducible suppression of functional p53.
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