Multitarget Compounds Active at a PPAR and Cannabinoid Receptor

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20110039808A1
SERIAL NO

12746008

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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There is a need for pharmaceutical compounds which have activity at, at least one of a PPAR and a cannabinoid receptor. Thus there are provided such compounds, wherein the compound comprises: a PPAR pharmacophore and a cannabinoid pharmacophore linked together by a moiety comprising a fused bicyclic ring comprising a five membered ring fused with a six membered ring or a six membered ring fused with a six membered ring; wherein the cannabinoid pharmacophore comprises the fused bicyclic ring; and the PPAR pharmacophore comprises a salicylic acid, alkoxybenzylacetic acid or a alkoxyphenylacetic acid functionality; and wherein the PPAR pharmacophore is linked to the bicyclic ring of the cannabinoid pharmacophore through a linker comprising an amine or an amide functional group.

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Patent Owner(s)

Patent OwnerAddress
NOGRA PHARMA LIMITEDDUBLIN 2

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baroni, Sergio Villa D'adda, IT 69 812
Bellinvia, Salvatore Pordenone, IT 56 633
Chavatte, Philippe Gondecourt, FR 9 76
Desreumaux, Pierre Marq En Baroeul, FR 16 96

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