IL-17RA-IL-17RB ANTAGONISTS AND USES THEREOF
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United States of America Patent
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Issued Date -
Mar 3, 2011
app pub date -
Feb 20, 2009
filing date -
Feb 21, 2008
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as various methods of use.
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