Process for depositing calcium phosphate therapeutic coatings with different release rates and a prosthesis coated via the process

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United States of America Patent

APP PUB NO 20110059149A1
SERIAL NO

12806608

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of coating a substrate including loading a calcium phosphate substance at a first crystallinity with a therapeutic agent; depositing the loaded calcium phosphate substance at the first crystallinity onto a least a portion of the substance; loading a calcium phosphate substance at a second, lower, crystallinity with a therapeutic agent; and depositing the loaded calcium phosphate substance at the second crystallinity onto the deposited loaded calcium phosphate substance at the first crystallinity to control and sustain a long-term osseointegration response and to control the release rate of the therapeutic substance from the calcium phosphate substance.

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Patent Owner(s)

Patent OwnerAddress
SPIRE CORPORATIONPATRIOTS PARK A CORP OF MA BEDFORD MA 01730

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aslani, Arash Acton, US 2 3
Burns, Jason E Cambridge, US 6 2
Kalkhoran, Nader M Tewksbury, US 11 836
Little, Marisa A Bedford, US 2 3
Tobin, Eric J North Andover, US 3 165

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