Methods for drug delivery comprising unfolding and folding proteins and peptide nanoparticles

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United States of America Patent

PATENT NO 9066870
SERIAL NO

12851600

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Abstract

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The present invention provides preparation methods of protein nanoparticles for in vivo delivery of pharmacologically active agents, wherein said methods are to encase pharmaceutically active agents into proteins or peptides to form nanoparticles by unfolding the protein, and subsequently refolding or assembling the protein to produce a pharmacologically active agent encased within a protein nanoparticle.

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Patent Owner(s)

  • NANJING UNIVERSITY;NANJING EFFECT PHARM DRUG DEVELOPMENT CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Dawei Jiangsu, CN 21 38
Gong, Guangming Jiangsu, CN 1 18
Hu, Yiqiao Jiangsu, CN 3 19
Li, Shaoling Sunnyvale, US 28 196
Tang, Xiaolei Jiangsu, CN 7 27
Tong, Chunhui Jiangsu, CN 1 18
Wu, Jinhui Jiangsu, CN 7 24
Zhu, Yan Jiangsu, CN 216 1237

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