POLYKETIDE SYNTHASE-NONRIBOSOMAL PEPTIDE SYNTHETASE GENE
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United States of America Patent
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Issued Date -
Mar 24, 2011
app pub date -
Oct 16, 2008
filing date -
Oct 19, 2007
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Abandoned
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Abstract
etc. as well as a transformant (strain), etc. that does not produce cyclopiazonic acid or a precursor thereof, cycloacetoacetyl L-tryptophan (CAT). A polynucleotide encodes the following polypeptides: (1) a polypeptide comprising the amino acid sequence depicted in SEQ ID NO: 2; (2) a polypeptide comprising an amino acid sequence with one or several amino acids deleted, substituted or added in the amino acid sequence depicted in SEQ ID NO: 2 and having a polyketide synthase-nonribosomal peptide synthetase activity; or (3) a polypeptide having 90% or more homology (identity) as an overall average with the amino acid sequence depicted in SEQ ID NO: 2 and having a polyketide synthase-nonribosomal peptide synthetase activity.
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