CHELATOR-TARGETING LIGAND CONJUGATES FOR CARDIOVASCULAR IMAGING

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United States of America Patent

APP PUB NO 20110085969A1
SERIAL NO

12900200

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are methods of imaging a site in a heart of a subject to detect cardiovascular disease that involve stressing a subject, administering to the stressed subject an effective amount of a radionuclide-labeled chelator-glucose analog conjugate, and imaging the heart of the subject by detecting a signal generated by the conjugate in the heart of the subject. Also disclosed are methods of imaging a peripheral blood vessel in a subject by using a detectable amount of a radionuclide-labeled chelator-glucose analog conjugate. Also disclosed are methods of distinguishing a false positive nuclear cardiology scan from a true positive nuclear cardiology scan, methods of diagnosing congestive heart failure or cardiac ischemia that involve imaging a subject that has been administered a radionuclide-labeled chelator-glucose analog conjugate, and methods to distinguish viable from nonviable myocardium.

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Patent Owner(s)

Patent OwnerAddress
CELL> POINT LLC4046 ROLLING TERRACE DRIVE SPRING TX 77388

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bryant, Jerry L Houston, US 3 28
Rollo, F David Saratoga, US 3 21

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