METHOD FOR PROFILING DRUG COMPOUNDS

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United States of America Patent

APP PUB NO 20110111980A1
SERIAL NO

12736468

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to systems and methods for testing kinase inhibition using an array of substrates, in particular protein kinase substrates, preferably immobilized on a porous matrix. More particularly, the method provides kinase inhibition profiles of kinase inhibitors using phosphorylation patterns. The present invention can therefore be used to predict the response of cells, tissues, organs and/or warm-blooded animals to a drug, to determine the clinical outcome of a drug therapy and for diagnostical and prognostical purposes.

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Patent Owner(s)

Patent OwnerAddress
PAMGENE B V5211 HH 'S-HERTOGENBOSCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Houtman, René Culemborn, NL 3 2
Ruijtenbeek, Robby Utrecht, NL 17 45

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