SELF-POWERED SMART DIAGNOSTIC DEVICES

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United States of America Patent

APP PUB NO 20110117668A1
SERIAL NO

12942919

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Devices and methods are provided for immobilizing a diagnostic target (e.g., indicative of a disease) from a solution (e.g., a biological fluid). The diagnostic target is first bound to a capture conjugate that includes a reversibly-associative polymer moieties attached to a first binding moiety that binds to the diagnostic target. Once the diagnostic target is bound to the capture conjugate, the solution is subjected to a change in heat and/or pH to cause the reversibly-associative polymer moieties to aggregate. The aggregates are then immobilized (e.g., via filtration).

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION4311 11TH AVENUE NE SUITE 500 SEATTLE WA 98105-4608

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Domingo-Villegas, Gonzalo Jose Seattle, US 3 86
Fomban, Nuvala Tofig Gana Seattle, US 1 5
Golden, Allison Seattle, US 1 5
Labarre, Paul Suquamish, US 3 18
Lai, Jriuan Seattle, US 7 96
Nash, Michael A Seattle, US 5 20
Stayton, Patrick S Seattle, US 50 995
Weigl, Bernhard H Seattle, US 52 4872

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