SERS NANOTAG ASSAYS WITH ENHANCED ASSAY KINETICS
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United States of America Patent
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Issued Date -
May 26, 2011
app pub date -
Jun 30, 2008
filing date -
Jun 29, 2007
priority date (Note) -
Abandoned
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Abstract
Methods and systems for the use of surface-enhanced Raman scattering nanotags (SERS nanotags) in various assay platforms which feature accelerated reaction kinetics. One embodiment includes a method detecting a substance of interest by associating a SERS nanotag with the substance of interest while accelerating the reaction kinetics of the association steps. This method also includes detecting a Raman spectrum of a reporter molecule associated with the SERS nanotag. The reaction kinetics of the assay may be accelerated by applying microwave radiation to the sample, heating the sample, agitating the sample, mixing the sample, vibrating the sample or other methods.
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