Importance

Loading Importance Indicators...

Abstract

Disclosed are methods and systems and methods for deep or superficial deep-brain stimulation using multiple therapeutic modalities. These impact multiple points in a neural circuit or one or multiple points in multiple neural circuits to produce Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. Modality examples are implanted deep-brain stimulators (DBS), Transcranial Magnetic Stimulation (TMS), transcranial Direct Current Stimulation (tDCS), implanted optical stimulation, focused ultrasound, RF stimulation, vagus nerve stimulation, other-implant stimulation, functional stimulation, and drugs. Some targets may be up-regulated and others down-regulated. Coordinated control is provided, as applicable, for control of the direction of the energy emission, intensity, session duration, frequency, pulse-train duration, phase, and numbers of sessions, if and as applicable, for neurormodulation of neural targets. Use of ancillary monitoring or imaging to provide feedback may be applied.

Loading the Abstract Image...

First Claim