Cardiac Muscle Regeneration Using Mesenchymal Stem Cells

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United States of America Patent

SERIAL NO

13012953

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Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.

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Patent Owner(s)

Patent OwnerAddress
MESOBLAST INTERNATIONAL SÀRL1217 MEYRIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gordon, Stephen L Columbia, US 26 845
Mackay, Alastair Morgan Timonium, US 16 608
Martin, Bradley J Ellicott City, US 15 365
Pittenger, Mark F Severna Park, US 45 1533

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