NEUTROKINE-ALPHA AND NEUTROKINE-ALPHA SPLICE VARIANT
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United States of America Patent
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Issued Date -
Jul 7, 2011
app pub date -
Dec 10, 2010
filing date -
Oct 25, 1996
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention.
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