Antitumor Immunization by Liposomal Delivery of Vaccine to the Spleen
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United States of America Patent
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Issued Date -
Jul 7, 2011
app pub date -
Jan 2, 2009
filing date -
Jan 2, 2008
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Abandoned
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Abstract
The present invention relates to methods for preventing, reducing or treating a variety of conditions, including cancer, and vaccines, compositions and liposomes used to elicit or amplify an immune response specific to the condition by delivering to the spleen of an individual a pegylated liposome construct having a diameter of greater than about 300 nm and including a therapeutic agent and an adjuvant for eliciting or amplifying the immune response.
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