Poly-Pegylated Protease Inhibitors

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United States of America Patent

SERIAL NO

12471875

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.

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Patent Owner(s)

Patent OwnerAddress
DYAX CORP300 SHIRE WAY LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ladner, Robert C Ijamsville, US 96 20298
Ley, Arthur C Newton, US 42 11502
Sato, Aaron K Somerville, US 45 1436
Stochl, Mark North Attleboro, US 5 166

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